Transfer of respiratory pathogens Drop size–dependent infectivity (ASIDE)
PROFESSOR: So let's build on this concept of diffusion of virions in droplets to understand how we would expect a size dependent infectivity of virions in different sized droplets. So an important concept in epidemiology that we will come to later is the infectivity, which is the probability that if a virion is transferred that it actually causes an infection in the host. That can be further broken down into a product of two probabilities. The first is that if the virus has escaped from the droplet, it actually causes an infection. And that's perhaps something which is roughly constant. It has to do with the physiology of the host. But then there is the escape of the virion from the droplet. And as we've already discussed, that's a strongly size dependent quantity. And from very large droplets, it's very difficult in a mucus droplet, especially, for the virion to diffuse out in a reasonable amount of time. And in fact, virions are typically found to ha...